Hair Restoration in Irvine, CA: Exosome Therapy & Selphyl PRFM
Exosome therapy and Selphyl PRFM hair restoration — physician-performed, root-cause treatment.
Last updated October 2026
What is PRP
Platelet-Rich Plasma (PRP) therapy is a non-surgical treatment designed to combat hair loss by stimulating natural hair growth. At Spectrum Skin Clinic, we offer PRP treatments tailored to your unique needs, helping you achieve a fuller, healthier head of hair.
Non-Surgical Hair Restoration in Irvine — Exosome Therapy & Selphyl PRFM
Hair loss affects millions of men and women — and most never find a solution that actually works. At our sister practice, Spectrum Skin Clinic, in the same Irvine office, Sabeen Munib M.D. offers two non-surgical hair restoration treatments: exosome therapy and Selphyl PRFM (platelet-rich fibrin matrix).
Whether you are seeing a widening part, thinning temples, or shedding that will not stop, we identify the root cause and build a treatment plan around your biology. Serving Irvine, Laguna Hills, Mission Viejo, Newport Beach, and across Orange County. Same-week consultations available.
Physician-Performed Hair Restoration — No Technicians, No Delegation.
Sabeen Munib, M.D. is a physician with over 15 years of experience in aesthetic and regenerative medicine. She personally performs every hair restoration treatment at Spectrum Skin Clinic — no nurses, no technicians, no delegation.
Dr. Munib considers systemic factors most aesthetic clinics overlook: hormonal imbalances, thyroid issues, iron deficiency, and GLP-1-induced telogen effluvium. As a practice that also offers Mounjaro and Ozempic, we are uniquely positioned to manage GLP-1-related hair loss proactively.
Every treatment plan starts with a thorough evaluation — not a sales pitch. You will leave your consultation knowing exactly what is causing your hair loss and what to expect from treatment.
"I had been losing hair for three years and tried everything. After four exosome sessions with Dr. Munib I finally have real regrowth — not just less shedding. She was the first doctor who actually explained why it was happening."
— Sarah, Irvine, CA
Hair Loss Conditions Dr. Munib Treats
Our treatments work best when follicles are still present but dormant or miniaturized. Dr. Munib treats the following conditions:
- Androgenetic alopecia — male and female pattern baldness driven by genetics and DHT sensitivity
- Telogen effluvium — sudden or diffuse shedding triggered by stress, illness, surgery, or childbirth
- GLP-1-related hair loss — Mounjaro, Ozempic, Wegovy, and Zepbound can trigger shedding from rapid weight loss
- Postpartum hair loss — hormonal shifts after pregnancy causing significant shedding
- Post-transplant maintenance — PRFM and exosome therapy support transplanted follicle survival
- Alopecia areata — patchy autoimmune hair loss; Dr. Munib evaluates each case individually
Patients with completely bald areas where follicles have been permanently destroyed may not achieve full regrowth. Dr. Munib gives you an honest assessment at consultation.
What Is Exosome Therapy for Hair Loss?
Exosomes are biological messengers from stem cells.
Exosomes are nano-sized extracellular vesicles naturally released by stem cells. They carry growth factors, proteins, and RNA signals that instruct dormant hair follicles to wake up, rebuild, and produce new hair.
What they do to your follicles.
At Spectrum Skin Clinic, exosomes are placed after microneedling and injected into the scalp when needed. The growth factors they deliver — FGF, VEGF, and EGF — extend the active growth phase of the hair cycle, increase follicular density, and improve scalp circulation.
No incisions. No anesthesia. No recovery time. Most patients return to normal activity the same day.
Exosome therapy tends to produce faster, more pronounced results than standard PRP — particularly for moderate-to-advanced hair loss — due to its higher concentration of growth factors and RNA signaling molecules.
Selphyl PRFM: The Most Advanced Form of PRP for Hair Restoration
At Spectrum Skin Clinic, Dr. Munib uses Selphyl PRFM, not standard PRP. Selphyl is an FDA-cleared system that creates a fibrin matrix scaffold around concentrated platelets from your own blood, releasing growth factors over days rather than hours.
Why this matters: standard PRP disperses quickly after injection. The Selphyl fibrin matrix holds platelets in place at the follicle, delivering a longer, stronger regenerative signal. Clinical studies show measurable improvements in hair count, shaft diameter, and scalp coverage after a series of 3 to 4 treatments.
The process uses a small blood draw, the Selphyl centrifugation system, and precise scalp injection. No additives — just your own biology, optimized. Spaced 4 to 6 weeks apart.
From Consultation to Recovery: Your Hair Restoration Appointment
Consultation: Dr. Munib reviews your health history, hair loss pattern, and likely cause. She examines follicular density and recommends exosome therapy, Selphyl PRFM, or a combined protocol based on your specific situation.
Treatment: Topical numbing cream is applied first. Exosomes or PRFM are injected in a precise grid pattern targeting areas of thinning. The procedure takes 45 to 60 minutes. No cutting, no sedation, no bandaging.
Immediately after: Mild redness or tenderness for 24 to 48 hours. You can wash your hair and return to normal activity the same day.
Results timeline: Reduced shedding is typically the first change, often within weeks. New hair growth becomes visible at months 3 to 4. Most significant density improvement between months 5 and 9. Full results by 9 to 12 months.
Most patients complete 3 to 4 sessions in the initial series, then choose maintenance every 6 to 12 months.
See Real Hair Restoration Results
Related Treatments at The Pur Health
- GLP-1 Weight Loss in Irvine — Mounjaro, Zepbound, Ozempic, and Wegovy. Physician-managed weight loss with proactive hair loss monitoring.
- Hormone Replacement in Irvine — Hormonal imbalances are a common cause of hair loss. Dr. Munib evaluates both together.
- Skinvive by Juvéderm in Irvine — Skin quality and scalp health treatments available alongside hair restoration.
Ready to Stop Hair Loss? Book a Consultation in Irvine.
Serving Irvine, Laguna Hills, Mission Viejo, Newport Beach, Lake Forest, and all of Orange County. Same-week appointments available.
Every consultation includes a full scalp evaluation and honest assessment — not a sales pitch. Call (949) 647-5234 or book online.
Why is my hair thinning? The medical causes checked first
Thinning hair often has a medical cause that treatment on the scalp will not fix. At The Pur Health, Dr. Munib looks for these first, usually with a short history and blood work.
- Thyroid problems
- Low iron stores, vitamin D or B12
- Hormone changes around menopause, after pregnancy, or with PCOS
- Fast weight loss, including on GLP-1 medicines
- A recent illness, high fever, surgery or major stress
These visits and labs are medical care. We are in-network with most PPO plans, and HSA and FSA cards are accepted.
Hair loss after GLP-1 weight loss or menopause
Losing 20 pounds or more can trigger heavy shedding a few months later. Hair loss is a listed side effect of Wegovy and Zepbound. This kind of shedding usually settles on its own, and hair often returns to its normal fullness within 6 to 9 months.
After menopause, many women notice a wider part or thinning on top. That is often female pattern hair loss, which does not settle on its own and responds better the earlier it is treated.
If you are on a GLP-1
Dr. Munib checks protein intake, iron and vitamin levels, and the pace of your weight loss, and adjusts your plan if needed.
If shedding does not settle
Hair that keeps thinning after 6 months, or a widening part, is worth treating directly at Spectrum Skin Clinic.
Hair restoration: sessions, downtime and cost
Sessions
Treatments such as Selphyl PRFM or exosome hair treatment are usually a short series several weeks apart, with occasional maintenance after.
Downtime
Minimal. The scalp may be tender or red for a day or two, and most people go back to normal activity the same day.
Results
Less shedding tends to come first. New growth takes at least a few months to show, and results vary with the cause.
Cost
Hair restoration is cosmetic and not covered by insurance. It is quoted at your consultation at Spectrum Skin Clinic.
Full hair restoration details at Spectrum Skin Clinic
Hair restoration is performed by Sabeen Munib M.D. at our sister practice, Spectrum Skin Clinic, in the same building. Treatment options and before and after photos are on the Spectrum hair restoration page.
Full details at Spectrum Skin Clinic
This treatment with Sabeen Munib M.D. is part of Spectrum Skin Clinic, our sister practice in the same Irvine office at 114 Pacifica. The full treatment page is there.
Sabeen Munib M.D.
MD · Residency at the University of Minnesota
Dr. Munib has cared for patients in Irvine and Orange County for more than 15 years. She focuses on preventive care, chronic disease management and whole-person wellness, and she takes the time to explain what she finds.
- Speaks Urdu and Hindi; our team also speaks Arabic, Farsi and Tagalog
- Sees adults and teens 12 and older
What our patients say
“I've been with Dr.Munib for nearly 10 years and she's been absolutely incredible. She's always available and goes out of her way to help. She's incredibly responsive and has helped me with issues that other specialists couldn't solve. It's so important to have a doctor who is always there for you and goes above and beyond to help and I found that with Dr.Munib. I can't recommend her enough! She's simply amazing.”
“I have had a couple of RF micro needling treatments and am so pleased with my results! Dr. Munib provides excellent and up to date guidance based on your skin care needs. She is also a great primary care physician who takes the time to listen and know her patients.”
“Dr. Munib is an amazing doctor. She listens to your health concerns and addresses them right away. She is very kind and takes her time to listen and explain everything. I’ve always been anxious to visit a doctor’s office, so I’m glad I found Dr. Munib because she is the best!”
More skin & hair care services
LED light therapySkin After Weight LossSkin Peptides (AnteAGE)Facial MassageLymphatic DrainageAll skin & hair care →Frequently asked questions
Questions are welcome. Our team is happy to help before you book.
Call (949) 647-5234What is the difference between exosome therapy and Selphyl PRFM?
Selphyl PRFM uses a fibrin matrix scaffold around concentrated platelets from your own blood, releasing growth factors over an extended period — longer-lasting than standard PRP. Exosome therapy uses lab-derived stem cell vesicles with a higher concentration of growth factors and RNA signals. PRFM is excellent for mild-to-moderate hair loss; exosomes are preferred for moderate-to-advanced cases. Dr. Munib may recommend combining both for maximum results.
How many sessions do I need?
Most patients start with 3 to 4 treatments spaced 4 to 6 weeks apart. Exosome therapy may produce meaningful results in fewer sessions due to its higher growth factor concentration. After the initial series, maintenance every 6 to 12 months sustains density and prevents further thinning.
How soon will I see hair regrowth results?
Reduced shedding is usually the first change, often within weeks of the first treatment. New hair growth typically becomes visible at months 3 to 4, with the most significant improvement in density and thickness between months 5 and 9. Full results from the initial series are usually seen by 9 to 12 months.
Is exosome hair therapy safe?
Yes. Exosomes are biocompatible and do not trigger immune responses. The procedure involves only scalp injections — no incisions, no anesthesia, no systemic medication. Side effects are typically limited to mild redness or tenderness at injection sites, resolving within 24 to 48 hours.
Does hair restoration hurt?
Topical numbing cream is applied to the scalp before the procedure, making it well-tolerated by most patients. The injections are typically described as mild pressure or light pinching. Most patients are comfortable throughout the 45 to 60 minute appointment.
How much does hair restoration cost in Irvine?
Pricing depends on whether you receive exosome therapy, Selphyl PRFM, or a combination protocol, and the number of sessions required. Dr. Munib provides full transparent pricing at your consultation with no hidden fees. Package pricing is available for multi-session protocols. Hair restoration is typically not covered by insurance.
Can Ozempic, Wegovy or Zepbound cause hair loss?
Yes, hair loss is a known side effect, most likely from fast weight loss. It is usually temporary, and hair often returns to normal fullness within 6 to 9 months.
What blood tests are done for hair loss?
Commonly thyroid tests, iron stores (ferritin), a blood count and vitamin D, plus hormone tests when the pattern suggests it. Dr. Munib chooses them based on your history.
Is hair loss after menopause permanent?
Not always. Shedding from a trigger often settles, but female pattern thinning tends to continue without treatment, so it is worth assessing early.
How many hair restoration sessions will I need?
Most people start with a short series spaced several weeks apart, then maintenance. Dr. Munib sets the plan at Spectrum Skin Clinic based on your cause and pattern.
Is there downtime after PRP or PRFM for hair?
Very little. Mild tenderness or redness for a day or two is common, and you can usually go back to your day right after.
Does insurance cover hair restoration?
No, hair restoration is cosmetic. The medical workup for the cause, such as visits and labs, can often be billed to your PPO plan.
Have any Questions? Feel Free To Contact Sabeen Munib M.D.
Get in touch and our team will call or email you. You can also call (949) 647-5234.